npde

Class "NpdeData" representing the structure of the longitudinal data

Class "NpdeObject"

Class "NpdeRes"

Class "NpdeSimData" representing the structure of the longitudinal data

Compute normalised prediction distribution errors

Compute P(y_ij<LOQ) for all observations

Internal functions used to compute normalised prediction distribution errors (npde)

Internal functions used to compute prediction discrepancies

Default plots for a NpdeObject object

Compute distribution of pd/npde using simulations

Get/set methods for NpdeData object

Goodness-of-fit tests for npde

Kurtosis

Normalised prediction distribution errors for nonlinear mixed-effect models

Internal functions used to produce prediction intervals

Method used to handle censored data

Decorrelation methods in npde

Save the graphs for a NpdeObject object to a file

Main npde function

Covariate diagnostic plots

Plot a NpdeData object

Diagnostic plots

Distribution plots of pd/npde

Plot of the probability that the observations are below the LOQ

Plots for pd and npde

################# Scatterplots - VPC, scatterplots versus independent variable, predictions, covariates ################### Scatterplots and VPC

Select plot for a NpdeObject object

Plots split by covariate for a NpdeObject object

Save the results contained in a NpdeObject object to a file

Set options for an NpdeObject

Creates a NpdeData object

Creates a NpdeSimData object

Interactive menu to set the options for the npde() function

Plots a NpdeData object

Plots a NpdeObject object

Plots a NpdeRes object

Prints objects from the npde package

Read data into structures (internal)

Replace graphical options

Set graphical preferences

Displays npde objects

Contents of an object

Simulated data for the computation of normalised prediction distribution errors in the theophylline dataset

Skewness

Subsetting a NpdeData object

Summary of a NpdeData object

Pharmacokinetics of theophylline

Simulated HIV viral loads in HIV patients

Pharmacokinetics of warfarin