npde: compute.ploq – R documentation

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compute.ploq

Compute P(y_ij<LOQ) for all observations

Description

For each observation in the dataset, computes the probability to be below LOQ using the simulations under the model. This is generally performed automatically.

Usage

compute.ploq(npdeObject)

Arguments

npdeObject

an object returned by a call to npde or autonpde

Value

an object of class NpdeObject with a component ploq in the ["results"] slot

Author(s)

Emmanuelle Comets <emmanuelle.comets@bichat.inserm.fr>

References

K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036–49, 2006.