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computenpde

Internal functions used to compute normalised prediction distribution errors (npde)


Description

Functions used by npde and autonpde to compute prediction discrepancies (not intended for the end-user).

Usage

computenpde(npdeObject,...)

Arguments

npdeObject

an object of class NpdeObject

...

additional options to modify

Details

These functions are normally not called by the end-user.

Value

an object of class NpdeObject; the results slot will now include prediction discrepancies (npde) as well as decorrelated observed data, while the sim.data slot will now include decorrelated simulated data

Author(s)

Emmanuelle Comets <emmanuelle.comets@bichat.inserm.fr>

References

K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036–49, 2006.

See Also


npde

Normalised Prediction Distribution Errors for Nonlinear Mixed-Effect Models

v3.1
GPL (>= 2)
Authors
Emmanuelle Comets [aut, cre] (<https://orcid.org/0000-0002-9150-9886>), Karl Brendel [ctb], Thi Huyen Tram Nguyen [ctb], Romain Leroux [ctb], France Mentre [ctb]
Initial release
2021-04-07

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