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npde.plot.loq

Plot of the probability that the observations are below the LOQ


Description

Plots the probability that the observations are below the LOQ along with the model predicted interval

Usage

npde.plot.loq(npdeObject,xaxis="x",nsim=200,...)

Arguments

npdeObject

an object returned by a call to npde or autonpde

xaxis

a string character, one of "x" (to plot P(Y<LOQ) versus the value of the independent predictor) or "ypred" (versus the value of the population predictions). Defaults to "x"

nsim

number of simulations to be used for the computation of the prediction interval

...

additional arguments to be passed on to the function, to control which metric (npde, pd, npd) is used or to override graphical parameters (see the PDF document for details, as well as set.plotoptions)

Value

a ggplot object or a list of ggplot objects (grobs)

Author(s)

Emmanuelle Comets <emmanuelle.comets@bichat.inserm.fr>

References

K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre. Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide. Pharmaceutical Research, 23:2036–49, 2006.

See Also


npde

Normalised Prediction Distribution Errors for Nonlinear Mixed-Effect Models

v3.1
GPL (>= 2)
Authors
Emmanuelle Comets [aut, cre] (<https://orcid.org/0000-0002-9150-9886>), Karl Brendel [ctb], Thi Huyen Tram Nguyen [ctb], Romain Leroux [ctb], France Mentre [ctb]
Initial release
2021-04-07

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