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ss2x2ci

Sample size using a confidence interval of previous 2x2 study


Description

It calculates sample size for the bioequivalence test on ratio using a confidence interval of previous 2x2 study.

Usage

ss2x2ci(n1, n2, LL, UL, Alpha = 0.1)

Arguments

n1

Subject count of group 1

n2

Subject count of group 2

LL

Lower limit of the confidence interval of geometric mean ratio (Test/Reference)

UL

Upper limit of the confidence interval of geometric mean ratio (Test/Reference)

Alpha

Alpha level. This means (1 - alpha/2)*100 % confidence interval is given

Details

It calculates sample size (n per group) with CV, Alpha, and Beta for bioequivalence test.

Value

Returns sample size (n per group) for bioequivalence test with ratio criteria.

Author(s)

Kyun-Seop Bae k@acr.kr

Examples

ss2x2ci(12, 13, 0.85, 1.11)

BE

Bioequivalence Study Data Analysis

v0.1.2
GPL-3
Authors
Kyun-Seop Bae [aut]
Initial release

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