Description

A randomized control trial in which both survival and longitudinal data were collected to examine the development of prothrombin index over time and its relationship with the survival outcome. 488 patients were randomly allocated to prednisone (251) or placebo (237) and followed until death or end of the study. liver.long only contains the longitudinal data of the trial, with one row per prothrombin index measurement.

Format

A data frame with 2968 observations on the following 3 variables.

ID

patient ID, there are 488 patients in total.

obstime

time points at which the longitudinal measurements, i.e. prothrombin index, are recorded.

proth

prothrombin index measured at obstime.

Source

Andersen, P. K., Borgan O., Gill, R. D. and Kieding, N. (1993) Statistical Models Based on Counting Processes. New York: Springer.

References

Henderson, R., Diggle, P. and Dobson, A. (2002) Identification and efficacy of longitudinal markers for survival. Biostatistics 3, 33–50

See Also

liver, liver.surv

Examples