PwrGSD

Calculate Power in a Group Sequential Design

The Lan-Demets method of Boundary Construction

The O'Brien-Fleming Alpha Spending Function

The Wang-Tsiatis Power Alpha Spending Function

The Pocock Alpha Spending Function

The Stochastic Curtailment method of Boundary Construction

The Haybittle method of Boundary Construction

Create a skeleton compound PwrGSD object

Extract the Power results

Convert a "PwrGSD" object to a "boundaries" object

Create a subset of a "cpd.PwrGSD" object

Plot Method for cpd.PwrGSD objects

Computes efficacy and futility boundaries

Conditional type I and type II error probabilities given current value of the test statistic

Verifies the results of "GrpSeqBnds" via simulation

Weighted log-rank test

Weighted Integrated Survival function test

Aggregated Hazard

My Survfit

Stack a dataset

Convert CDF Odds Ratio to Logged Relative Risks

Calender year rates to Study Year Rates

Cumulative-risk ratios to risk ratios

Relative cumulative mortality to Relative Risk

Relative risk to Relative Cumulative Mortality

Lookup values for a piecewise constant function

Mayo Clinic Lung Cancer Data

A utility function for forming differences

The paste operator

Converts a stochastic curtailment boundary (conditional type I or II error probability) into a (efficacy or futility) boundary on the standardized Z scale

A function for computing the probability density for the group sequentially monitored test statistic.

A function for computing the bias adjusted point estimate for a statistic observed to cross the efficacy boundary.

Function to extract the 'detail' component from a PwrGSD object