Functions to identify Homozygous-by-Descent (HBD) segments associated with runs of homozygosity (ROH) and to
estimate individual autozygosity (or inbreeding coefficient). HBD segments and autozygosity are assigned to multiple HBD classes
with a model-based approach relying on a mixture of exponential distributions. The rate of the exponential distribution is distinct
for each HBD class and defines the expected length of the HBD segments. These HBD classes are therefore related to the age of the
segments (longer segments and smaller rates for recent autozygosity / recent common ancestor). The functions allow to estimate the
parameters of the model (rates of the exponential distributions, mixing proportions), to estimate global and local autozygosity
probabilities and to identify HBD segments with the Viterbi decoding. The method is fully described in Druet and Gautier (2017)
<doi:10.1111/mec.14324>.

Partitioning of Individual Autozygosity into Multiple
Homozygous-by-Descent Classes

package-ubuntu-20.04-r-4.0.5#cran#RZooRoH-0.3.0

<p>The results were obtained by running the default model (10 classes
with pre-defined rates) on 110 individuals genotyped at 37465 SNPs.
</p>

package-ubuntu-20.04-r-4.0.5#cran#RZooRoH-0.3.0#docs#soay_mix10r

soay_mix10r

Description

Usage

Format

RZooRoH

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