Functions to identify Homozygous-by-Descent (HBD) segments associated with runs of homozygosity (ROH) and to
estimate individual autozygosity (or inbreeding coefficient). HBD segments and autozygosity are assigned to multiple HBD classes
with a model-based approach relying on a mixture of exponential distributions. The rate of the exponential distribution is distinct
for each HBD class and defines the expected length of the HBD segments. These HBD classes are therefore related to the age of the
segments (longer segments and smaller rates for recent autozygosity / recent common ancestor). The functions allow to estimate the
parameters of the model (rates of the exponential distributions, mixing proportions), to estimate global and local autozygosity
probabilities and to identify HBD segments with the Viterbi decoding. The method is fully described in Druet and Gautier (2017)
<doi:10.1111/mec.14324>.

Partitioning of Individual Autozygosity into Multiple
Homozygous-by-Descent Classes

package-ubuntu-20.04-r-4.0.5#cran#RZooRoH-0.3.0

The allele frequencies of the first allele were computed in a larger sample.

A data frame with 6370 rows and one variable.

<dl>
<dt>frq</dt>
<dd>
The allele frequencies estimated for the first allele
</dd>
</dl>

package-ubuntu-20.04-r-4.0.5#cran#RZooRoH-0.3.0#docs#typsfrq

typsfrq

Description

Usage

Format

RZooRoH

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