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Estimate the effective number of tests for Bonferroni correction


Description

Estimate the effective number of tests for Bonferroni correction using the minimum achievable p-values (MAP).

Usage

Get_EffectiveNumberTest(MAP, alpha=0.05, Is.MidP=TRUE)

Arguments

MAP

a vector of the minimum achievable p-values (MAP).

alpha

a significant level.

Is.MidP

a logical value indicating whether p-values are mid-p-values.

Value

Effective number of test for Bonferroni correction at the level alpha. MAP can be obtained from SKATBinary functions.

Author(s)

Seunggeun Lee

References

Lee, S., Fuchsberger, C., Kim, S., Scott, L. (2015) An efficient resampling method for calibrating single and gene-based rare variant association analysis in case-control studies. Biostatistics, in press.


SKAT

SNP-Set (Sequence) Kernel Association Test

v2.0.1
GPL (>= 2)
Authors
Seunggeun (Shawn) Lee and Zhangchen Zhao, with contributions from Larisa Miropolsky and Michael Wu
Initial release
2020-10-20

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