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GroupCorrelation

Compute the correlation of features broken down by groups with another covariate


Description

Compute the correlation of features broken down by groups with another covariate

Usage

GroupCorrelation(
  object,
  assay = NULL,
  slot = "scale.data",
  var = NULL,
  group.assay = NULL,
  min.cells = 5,
  ngroups = 6,
  do.plot = TRUE
)

Arguments

object

Seurat object

assay

Assay to pull the data from

slot

Slot in the assay to pull feature expression data from (counts, data, or scale.data)

var

Variable with which to correlate the features

group.assay

Compute the gene groups based off the data in this assay.

min.cells

Only compute for genes in at least this many cells

ngroups

Number of groups to split into

do.plot

Display the group correlation boxplot (via GroupCorrelationPlot)

Value

A Seurat object with the correlation stored in metafeatures


Seurat

Tools for Single Cell Genomics

v4.0.1
GPL-3 | file LICENSE
Authors
Andrew Butler [ctb] (<https://orcid.org/0000-0003-3608-0463>), Saket Choudhary [ctb] (<https://orcid.org/0000-0001-5202-7633>), Charlotte Darby [ctb] (<https://orcid.org/0000-0003-2195-5300>), Jeff Farrell [ctb], Christoph Hafemeister [ctb] (<https://orcid.org/0000-0001-6365-8254>), Yuhan Hao [ctb] (<https://orcid.org/0000-0002-1810-0822>), Paul Hoffman [aut, cre] (<https://orcid.org/0000-0002-7693-8957>), Jaison Jain [ctb] (<https://orcid.org/0000-0002-9478-5018>), Efthymia Papalexi [ctb] (<https://orcid.org/0000-0001-5898-694X>), Patrick Roelli [ctb], Rahul Satija [ctb] (<https://orcid.org/0000-0001-9448-8833>), Karthik Shekhar [ctb], Avi Srivastava [ctb] (<https://orcid.org/0000-0001-9798-2079>), Tim Stuart [ctb] (<https://orcid.org/0000-0002-3044-0897>), Kristof Torkenczy [ctb] (<https://orcid.org/0000-0002-4869-7957>), Shiwei Zheng [ctb] (<https://orcid.org/0000-0001-6682-6743>), Satija Lab and Collaborators [fnd]
Initial release
2021-03-17

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