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MetaFeature

Aggregate expression of multiple features into a single feature

Description

Calculates relative contribution of each feature to each cell for given set of features.

Usage

MetaFeature(
  object,
  features,
  meta.name = "metafeature",
  cells = NULL,
  assay = NULL,
  slot = "data"
)

Arguments

object

A Seurat object
features

List of features to aggregate
meta.name

Name of column in metadata to store metafeature
cells

List of cells to use (default all cells)
assay

Which assay to use
slot

Which slot to take data from (default data)

Value

Returns a Seurat object with metafeature stored in objct metadata

Examples

data("pbmc_small")
pbmc_small <- MetaFeature(
  object = pbmc_small,
  features = c("LTB", "EAF2"),
  meta.name = 'var.aggregate'
)
head(pbmc_small[[]])
Seurat

Tools for Single Cell Genomics

v4.0.1
GPL-3 | file LICENSE
Authors
Andrew Butler [ctb] (<https://orcid.org/0000-0003-3608-0463>), Saket Choudhary [ctb] (<https://orcid.org/0000-0001-5202-7633>), Charlotte Darby [ctb] (<https://orcid.org/0000-0003-2195-5300>), Jeff Farrell [ctb], Christoph Hafemeister [ctb] (<https://orcid.org/0000-0001-6365-8254>), Yuhan Hao [ctb] (<https://orcid.org/0000-0002-1810-0822>), Paul Hoffman [aut, cre] (<https://orcid.org/0000-0002-7693-8957>), Jaison Jain [ctb] (<https://orcid.org/0000-0002-9478-5018>), Efthymia Papalexi [ctb] (<https://orcid.org/0000-0001-5898-694X>), Patrick Roelli [ctb], Rahul Satija [ctb] (<https://orcid.org/0000-0001-9448-8833>), Karthik Shekhar [ctb], Avi Srivastava [ctb] (<https://orcid.org/0000-0001-9798-2079>), Tim Stuart [ctb] (<https://orcid.org/0000-0002-3044-0897>), Kristof Torkenczy [ctb] (<https://orcid.org/0000-0002-4869-7957>), Shiwei Zheng [ctb] (<https://orcid.org/0000-0001-6682-6743>), Satija Lab and Collaborators [fnd]
Initial release
2021-03-17

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