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n_dist.FarringtonManning

Distribution of the Sample Size


Description

Calculates the distribution of the total sample sizes of designs with blinded sample size recalculation for different values of the nuisance parameter or of n1.

Usage

## S4 method for signature 'FarringtonManning'
n_dist(
  design,
  n1,
  nuisance,
  summary,
  plot,
  allocation = c("exact", "approximate"),
  ...
)

Arguments

design

Object of class FarringtonManning created by setupFarringtonManning.

n1

Either the sample size of the first stage (if recalculation = TRUE or the toal sample size (if recalculation = FALSE).

nuisance

Value of the nuisance parameter. For the Farrington-Manning test this is the overall response rate.

summary

Logical. If TRUE (default) a summary of the sample size distribution is printed. If FALSE all sample sizes are printed.

plot

Should a plot of the sample size distribution be drawn?

allocation

Whether the allocation ratio should be preserved exactly (exact) or approximately (approximate).

...

Further optional arguments.

Details

Only sample sizes that occur with a probability of at least 0.01 considered.

The method is only vectorized in either nuisance or n1.

Value

Summary and/or plot of the sample size distribution for each nuisance parameter and every value of n1.

Examples

d <- setupFarringtonManning(alpha = 0.025, beta = 0.2, r = 1, delta = 0, delta_NI = 0.25)
n_dist(d, n1 = 30, nuisance = 0.2, summary = TRUE, plot = FALSE)

blindrecalc

Blinded Sample Size Recalculation

v0.1.2
MIT + file LICENSE
Authors
Lukas Baumann [aut], Maximilian Pilz [aut, cre], Institute of Medical Biometry and Informatics - University of Heidelberg [cph]
Initial release

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