Stop based on probability of target tox interval
Stop based on probability of target tox interval
target
the target toxicity interval, e.g. c(0.2, 0.35)
prob
required target toxicity probability (e.g. 0.4
)
for reaching sufficient precision
# As example, here is the rule for: # stopping the study if the posterior probability that [0.2 =< Prob(DLT | dose) <= 0.35] # for the next best dose is above 0.5 myStopping <- StoppingTargetProb(target=c(0.2, 0.35), prob=0.5)
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