The class with the input for finding the next best MTD estimate
The class with the input for finding the next best MTD estimate
targetthe target toxicity probability
derivethe function which derives from the input, a vector of
posterior MTD samples called mtdSamples, the final next best MTD
estimate.
# In the example below the MTD is defined as the dose for which prob(DLE)=0.33 and
# we will use the 25th quantile of the posterior of MTD as our next best dose.
mtdNextBest <- NextBestMTD(target=0.33,
derive=
function(mtdSamples){
quantile(mtdSamples, probs=0.25)
})Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.