Dose-Finding by the Continual Reassessment Method
Provides functions to run the CRM and TITE-CRM in phase I trials and calibration tools for trial planning purposes.
Coherence of two-stage CRM
Executing the CRM
Model Sensitivity in the CRM
CRM Simulator
Calibrating an initial design
Sample size calculator for CRM trials
Calibrating prior DLT rates
Executing the TITE-CRM
TITE-CRM Simulator
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