Produce DTP flow diagram
dtpflow will produce a flow diagram of the possible paths for the next three cohorts of subjects.
dtpflow(dtptable, cohort.labels = c('C1', 'C2', 'C3'))dtptable |
a dataframe produced by calculate_dtps where cohort_sizes was of length 3. |
cohort.labels |
A vector of length 3, containing character strings for the cohort labels. |
The function will produce a visual flow diagram for the first three cohorts of the provided dataframe.
prior <- c(0.1, 0.2, 0.5)
target <- 0.15
prev_tox <- c(0, 0, 0)
prev_dose <- c(2, 2, 2)
cohort_sizes <- c(2, 3, 3)
next_dose = applied_crm(prior = prior, target = target,
tox = prev_tox, level = prev_dose)$mtd
dose_func <- applied_crm
DTP = calculate_dtps(next_dose, cohort_sizes, prev_tox = prev_tox,
prev_dose = prev_dose, dose_func = applied_crm,
prior = prior, target = target)
dtpflow(dtptable = DTP, cohort.labels = c('C1', 'C2', 'C3'))Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.