Unconditional marker simulation
Unconditional simulation of unlinked markers
simpleSim( x, N, alleles, afreq, ids, Xchrom = FALSE, mutmod = NULL, seed = NULL, verbose = TRUE )
x |
a |
N |
a positive integer: the number of markers to be simulated |
alleles |
a vector with allele labels. |
afreq |
a numeric vector of allele frequencies. If missing, the alleles are assumed to be equi-frequent. |
ids |
a vector containing ID labels of those pedigree members whose genotypes should be simulated. |
Xchrom |
a logical: X linked markers or not? |
mutmod |
a |
seed |
An integer seed for the random number generator (optional). |
verbose |
a logical. |
This simulation is done by distributing alleles randomly to all founders,
followed by unconditional gene dropping down throughout the pedigree (i.e.
for each non-founder a random allele is selected from each of the parents).
Finally the genotypes of any individuals not included in ids are removed.
a ped object equal to x in all respects except its MARKERS
entry, which consists of the N simulated markers.
Magnus Dehli Vigeland
x = nuclearPed(1) simpleSim(x, N = 3, afreq = c(0.5, 0.5)) y = cousinPed(1, child = TRUE) simpleSim(y, N = 3, alleles = LETTERS[1:10])
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