Exact Test of Hardy-Weinberg Equilibrium for 2-Allele Markers
Exact test of Hardy-Weinberg Equilibrium for 2 Allele Markers.
HWE.exact(x)
x |
Genotype object |
Object of class 'htest'.
This function only works for genotypes with exactly 2 alleles.
David Duffy davidD@qimr.edu.au with modifications by Gregory R. Warnes greg@warnes.net
Emigh TH. (1980) "Comparison of tests for Hardy-Weinberg Equilibrium", Biometrics, 36, 627-642.
example.data <- c("D/D","D/I","D/D","I/I","D/D", "D/D","D/D","D/D","I/I","") g1 <- genotype(example.data) g1 HWE.exact(g1) # compare with HWE.chisq(g1) g2 <- genotype(sample( c("A","C"), 100, p=c(100,10), rep=TRUE), sample( c("A","C"), 100, p=c(100,10), rep=TRUE) ) HWE.exact(g2)
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