Bladder cancer in mice
Female mice were continuously fed dietary concentrations of 2-Acetylaminofluorene (2-AAF), a carcinogenic and mutagenic derivative of fluorene. Serially sacrificed, dead or moribund mice were examined for tumors and dates of deaths were recorded. These data consist of the incidences of bladder neoplasms in the mice observed during 33 months.
data(bladder)
A data frame with 8 rows and 3 variables:
a numeric vector giving the dose, in parts per 10^4, of 2-AAF.
a numeric vector giving the number of mice exposed to each dose of 2-AAF.
a numeric vector giving the number of mice with bladder cancer for each dose of 2-AAF.
Zhang H. and Zelterman D. (1999) Binary Regression for Risks in Excess of Subject-Specific Thresholds. Biometrics 55, 1247-1251.
barplot(100*cancer/exposed ~ dose, beside=TRUE, data=bladder, col="red",
xlab="Dose of 2-AAF", ylab="% of mice with bladder cancer")Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.