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Frank2018invivo

Literature In Vivo Data on Doses Causing Neurological Effects

Description

Studies were selected from Table 1 in Mundy et al., 2015, as the studies in that publication were cited as examples of compounds with evidence for developmental neurotoxicity. There were sufficient in vitro toxicokinetic data available for this package for only 6 of the 42 chemicals.

Usage

Frank2018invivo

Format

A data.frame containing 14 rows and 16 columns.

Author(s)

Timothy J. Shafer

References

Frank, Christopher L., et al. "Defining toxicological tipping points in neuronal network development." Toxicology and Applied Pharmacology 354 (2018): 81-93.

Mundy, William R., et al. "Expanding the test set: Chemicals with potential to disrupt mammalian brain development." Neurotoxicology and Teratology 52 (2015): 25-35.

httk

High-Throughput Toxicokinetics

v2.0.4

GPL-3

Authors

John Wambaugh [aut, cre] (<https://orcid.org/0000-0002-4024-534X>), Robert Pearce [aut] (<https://orcid.org/0000-0003-3168-4049>), Caroline Ring [aut] (<https://orcid.org/0000-0002-0463-1251>), Greg Honda [aut] (<https://orcid.org/0000-0001-7713-9850>), Mark Sfeir [aut], Matt Linakis [aut] (<https://orcid.org/0000-0003-0526-2395>), Sarah Davidson [aut] (<https://orcid.org/0000-0002-2891-9380>), Miyuki Breen [ctb] (<https://orcid.org/0000-0001-8511-4653>), Shannon Bell [ctb], Xiaoqing Chang [ctb] (<https://orcid.org/0000-0003-0752-1848>), Jimena Davis [ctb], James Sluka [ctb] (<https://orcid.org/0000-0002-5901-1404>), Nisha Sipes [ctb] (<https://orcid.org/0000-0003-4203-6426>), Barbara Wetmore [ctb] (<https://orcid.org/0000-0002-6878-5348>), Woodrow Setzer [ctb] (<https://orcid.org/0000-0002-6709-9186>)

Initial release

2021-05-07