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get_rblood2plasma

Get ratio of the blood concentration to the plasma concentration.


Description

This function attempts to retrieve a measured species- and chemical-specific blood:plasma concentration ratio.

Usage

get_rblood2plasma(
  chem.name = NULL,
  chem.cas = NULL,
  dtxsid = NULL,
  species = "Human",
  default.to.human = FALSE
)

Arguments

chem.name

Either the chemical name or the CAS number must be specified.

chem.cas

Either the CAS number or the chemical name must be specified.

dtxsid

EPA's 'DSSTox Structure ID (https://comptox.epa.gov/dashboard) the chemical must be identified by either CAS, name, or DTXSIDs

species

Species desired (either "Rat", "Rabbit", "Dog", "Mouse", or default "Human").

default.to.human

Substitutes missing animal values with human values if true.

Details

A value of NA is returned when the requested value is unavailable. Values are retrieved from chem.physical_and_invitro.data. details than the description above ~~

Value

A numeric value for the steady-state ratio of chemical concentration in blood to plasma

Author(s)

Robert Pearce

Examples

get_rblood2plasma(chem.name="Bisphenol A")
get_rblood2plasma(chem.name="Bisphenol A",species="Rat")

httk

High-Throughput Toxicokinetics

v2.0.4
GPL-3
Authors
John Wambaugh [aut, cre] (<https://orcid.org/0000-0002-4024-534X>), Robert Pearce [aut] (<https://orcid.org/0000-0003-3168-4049>), Caroline Ring [aut] (<https://orcid.org/0000-0002-0463-1251>), Greg Honda [aut] (<https://orcid.org/0000-0001-7713-9850>), Mark Sfeir [aut], Matt Linakis [aut] (<https://orcid.org/0000-0003-0526-2395>), Sarah Davidson [aut] (<https://orcid.org/0000-0002-2891-9380>), Miyuki Breen [ctb] (<https://orcid.org/0000-0001-8511-4653>), Shannon Bell [ctb], Xiaoqing Chang [ctb] (<https://orcid.org/0000-0003-0752-1848>), Jimena Davis [ctb], James Sluka [ctb] (<https://orcid.org/0000-0002-5901-1404>), Nisha Sipes [ctb] (<https://orcid.org/0000-0003-4203-6426>), Barbara Wetmore [ctb] (<https://orcid.org/0000-0002-6878-5348>), Woodrow Setzer [ctb] (<https://orcid.org/0000-0002-6709-9186>)
Initial release
2021-05-07

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