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httkpop_biotophys_default

Convert HTTK-Pop-generated parameters to HTTK physiological parameters


Description

Convert HTTK-Pop-generated parameters to HTTK physiological parameters

Usage

httkpop_biotophys_default(indiv_dt)

Arguments

indiv_dt

The data.table object returned by httkpop_generate()

Value

A data.table with the physiological parameters expected by any HTTK model, including body weight (BW), hematocrit, tissue volumes per kg body weight, tissue flows as fraction of CO, CO per (kg BW)^3/4, GFR per (kg BW)^3/4, portal vein flow per (kg BW)^3/4, and liver density.

Author(s)

Caroline Ring

References

Ring, Caroline L., et al. "Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability." Environment International 106 (2017): 105-118


httk

High-Throughput Toxicokinetics

v2.0.4
GPL-3
Authors
John Wambaugh [aut, cre] (<https://orcid.org/0000-0002-4024-534X>), Robert Pearce [aut] (<https://orcid.org/0000-0003-3168-4049>), Caroline Ring [aut] (<https://orcid.org/0000-0002-0463-1251>), Greg Honda [aut] (<https://orcid.org/0000-0001-7713-9850>), Mark Sfeir [aut], Matt Linakis [aut] (<https://orcid.org/0000-0003-0526-2395>), Sarah Davidson [aut] (<https://orcid.org/0000-0002-2891-9380>), Miyuki Breen [ctb] (<https://orcid.org/0000-0001-8511-4653>), Shannon Bell [ctb], Xiaoqing Chang [ctb] (<https://orcid.org/0000-0003-0752-1848>), Jimena Davis [ctb], James Sluka [ctb] (<https://orcid.org/0000-0002-5901-1404>), Nisha Sipes [ctb] (<https://orcid.org/0000-0003-4203-6426>), Barbara Wetmore [ctb] (<https://orcid.org/0000-0002-6878-5348>), Woodrow Setzer [ctb] (<https://orcid.org/0000-0002-6709-9186>)
Initial release
2021-05-07

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