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physiology.data

Species-specific physiology parameters

Description

This data set contains values from Davies and Morris (1993) necessary to paramaterize a toxicokinetic model for human, mouse, rat, dog, or rabbit. The temperature for each species are taken from Robertshaw et al. (2004), Gordon (1993), and Stammers(1926).

Usage

physiology.data

Format

A data.frame containing 11 rows and 7 columns.

Author(s)

John Wambaugh and Nisha Sipes

Source

Wambaugh, John F., et al. "Toxicokinetic triage for environmental chemicals." Toxicological Sciences (2015): 228-237.

References

Davies, B. and Morris, T. (1993). Physiological Parameters in Laboratory Animals and Humans. Pharmaceutical Research 10(7), 1093-1095, 10.1023/a:1018943613122. Environment, in Dukes' Physiology of Domestic Animals, 12th ed., Reece W.O., Ed. Copyright 2004 by Cornell University. Stammers (1926) The blood count and body temperature in normal rats Gordon (1993) Temperature Regulation in Laboratory Rodents

httk

High-Throughput Toxicokinetics

v2.0.4

GPL-3

Authors

John Wambaugh [aut, cre] (<https://orcid.org/0000-0002-4024-534X>), Robert Pearce [aut] (<https://orcid.org/0000-0003-3168-4049>), Caroline Ring [aut] (<https://orcid.org/0000-0002-0463-1251>), Greg Honda [aut] (<https://orcid.org/0000-0001-7713-9850>), Mark Sfeir [aut], Matt Linakis [aut] (<https://orcid.org/0000-0003-0526-2395>), Sarah Davidson [aut] (<https://orcid.org/0000-0002-2891-9380>), Miyuki Breen [ctb] (<https://orcid.org/0000-0001-8511-4653>), Shannon Bell [ctb], Xiaoqing Chang [ctb] (<https://orcid.org/0000-0003-0752-1848>), Jimena Davis [ctb], James Sluka [ctb] (<https://orcid.org/0000-0002-5901-1404>), Nisha Sipes [ctb] (<https://orcid.org/0000-0003-4203-6426>), Barbara Wetmore [ctb] (<https://orcid.org/0000-0002-6878-5348>), Woodrow Setzer [ctb] (<https://orcid.org/0000-0002-6709-9186>)

Initial release

2021-05-07