kangar00: rewire_network – R documentation

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rewire_network

Rewires interactions in a pathway, which go through a gene not represented by any SNPs in the considered GWASdata dataset.

Description

Rewires interactions in a pathway, which go through a gene not represented by any SNPs in the considered GWASdata dataset.

Usage

## S4 method for signature 'pathway'
rewire_network(object, x)

Arguments

`object`	`pathway` object which's network `matrix` will be rewired
`x`	A `vector` of gene names, indicating which genes are not represented by SNPs in the considered `GWASdata` object and will be removed

Value

A pathway object including the rewired network matrix

Author(s)

Juliane Manitz, Stefanie Friedrichs

Examples

## Not run: 
data(hsa04020)
summary(hsa04020)
hsa04020_rewired <- rewire_network(hsa04020, x=c('ADCY3', 'CALML3','GNAQ'))
summary(hsa04020_rewired)

## End(Not run)

kangar00

Kernel Approaches for Nonlinear Genetic Association Regression

v1.4

GPL-2

Authors

Juliane Manitz [aut], Stefanie Friedrichs [aut], Patricia Burger [aut], Benjamin Hofner [aut], Ngoc Thuy Ha [aut], Saskia Freytag [ctb], Heike Bickeboeller [ctb]

Initial release

2020-02-12