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addNpde

NPDE calculation for nlmixr


Description

NPDE calculation for nlmixr

Usage

addNpde(
  object,
  updateObject = TRUE,
  table = tableControl(),
  ...,
  envir = parent.frame(1)
)

Arguments

object

nlmixr fit object

updateObject

Boolean indicating if original object should be updated. By default this is TRUE.

table

'tableControl()' list of options

...

Other ignored parameters.

envir

Environment that should be checked for object to update. By default this is the global environment.

Value

New nlmixr fit object

Author(s)

Matthew L. Fidler

Examples

one.cmt <- function() {
  ini({
    ## You may label each parameter with a comment
    tka <- 0.45 # Log Ka
    tcl <- log(c(0, 2.7, 100)) # Log Cl
    ## This works with interactive models
    ## You may also label the preceding line with label("label text")
    tv <- 3.45; label("log V")
    ## the label("Label name") works with all models
    eta.ka ~ 0.6
    eta.cl ~ 0.3
    eta.v ~ 0.1
    add.sd <- 0.7
  })
  model({
    ka <- exp(tka + eta.ka)
    cl <- exp(tcl + eta.cl)
    v <- exp(tv + eta.v)
    linCmt() ~ add(add.sd)
  })
}

f <- nlmixr(one.cmt, theo_sd, "saem")

# even though you may have forgotten to add the NPDE, you can add it to the data.frame:

f <- addNpde(f)

nlmixr

Nonlinear Mixed Effects Models in Population PK/PD

v2.0.4
GPL (>= 2)
Authors
Matthew Fidler [aut] (<https://orcid.org/0000-0001-8538-6691>), Yuan Xiong [aut], Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<https://orcid.org/0000-0001-9871-8616>), Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Daniel C. Dillon [ctb], Katharine Mullen [cph], Ben Goodrich [ctb]
Initial release

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