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bootdata

Bootstrap data


Description

Bootstrap data by sampling the same number of subjects from the original dataset by sampling with replacement.

Usage

bootdata(dat)

Arguments

dat

model data to be bootstrapped

Value

Bootstrapped data

Examples

specs <- list(fixed = lKA + lCL + lV ~ 1,
  random = pdDiag(lKA + lCL ~ 1),
  start = c(lKA = 0.5, lCL = -3.2, lV = -1))
set.seed(99)
nboot <- 5
cat("generating", nboot, "bootstrap samples...\n")
cmat <- matrix(NA, nboot, 3)
for (i in 1:nboot)
{
  # print(i)
  bd <- bootdata(theo_md)
  fit <- nlme_lin_cmpt(bd, par_model = specs, ncmt = 1)
  cmat[i, ] <- fit$coefficients$fixed
}
dimnames(cmat)[[2]] <- names(fit$coefficients$fixed)
print(head(cmat))

nlmixr

Nonlinear Mixed Effects Models in Population PK/PD

v2.0.4
GPL (>= 2)
Authors
Matthew Fidler [aut] (<https://orcid.org/0000-0001-8538-6691>), Yuan Xiong [aut], Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<https://orcid.org/0000-0001-9871-8616>), Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Daniel C. Dillon [ctb], Katharine Mullen [cph], Ben Goodrich [ctb]
Initial release

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