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initializeCovars

Initializing covariates before estimation


Description

Initializing covariates before estimation

Usage

initializeCovars(
  fitobject,
  fstring,
  covNames,
  initialEst,
  initialEstLB,
  initialEstUB
)

Arguments

fitobject

an nlmixr 'fit' object

fstring

a string giving the entire expression for the model function string

covNames

a list of covariate names (parameters) that need to be estimates

initialEst

the initial estimate for the covariate parameters to be estimated; default is 0

initialEstLB

a lower bound for the covariate parameters to be estimated; default is -Inf

initialEstUB

an upper bound for the covariate parameters to be estimated; default is Inf

Value

updated model object with the modified initial values

Author(s)

Vipul Mann, Matthew Fidler


nlmixr

Nonlinear Mixed Effects Models in Population PK/PD

v2.0.4
GPL (>= 2)
Authors
Matthew Fidler [aut] (<https://orcid.org/0000-0001-8538-6691>), Yuan Xiong [aut], Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<https://orcid.org/0000-0001-9871-8616>), Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Daniel C. Dillon [ctb], Katharine Mullen [cph], Ben Goodrich [ctb]
Initial release

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