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lin_cmt

concentrations from a linear compartment model

Description

concentrations from a linear compartment model by close-form solutions

Usage

lin_cmt(
  obs_time,
  dose_time,
  dose,
  Tinf,
  params,
  oral,
  infusion,
  ncmt,
  parameterization
)

Arguments

obs_time

times at which an observation is desired
dose_time

times at which doses are given
dose

a vector of doses
Tinf

a vector of infusion duration
params

model-appropriate parameters per parameterization
oral

logical, whether oral absorption is true
infusion

logical, whether infusion is true
ncmt

number of compartments
parameterization

type of parameterization, 1=clearance/volume, 2=micro-constants

Value

calculated concentrations

nlmixr

Nonlinear Mixed Effects Models in Population PK/PD

v2.0.4
GPL (>= 2)
Authors
Matthew Fidler [aut] (<https://orcid.org/0000-0001-8538-6691>), Yuan Xiong [aut], Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<https://orcid.org/0000-0001-9871-8616>), Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Daniel C. Dillon [ctb], Katharine Mullen [cph], Ben Goodrich [ctb]
Initial release

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