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nlmixr

nlmixrUI.nlmefun

Create the nlme parameter transform function from the UI object.

Description

Create the nlme parameter transform function from the UI object.

Usage

nlmixrUI.nlmefun(object, mu.type = c("thetas", "covariates", "none"))

Arguments

object

UI object
mu

Is the model mu referenced?

  • With the "thetas" only the population parameters are mu-referenced; All covariates are included in the model parameter function. The between subject variability pieces are specified in the random specs parameter.

  • With the "covariates" option, the population parameters are mu referenced and covariates are removed from the model function. The covariates will be specified used in the fixed effects parameterization of nlme, like list(lKA+lCL~1, lV~WT)

  • With the "none" option, the model function is given to nlme without any modification.

Value

Parameter function for nlme

Author(s)

Matthew L. Fidler

nlmixr

Nonlinear Mixed Effects Models in Population PK/PD

v2.0.4
GPL (>= 2)
Authors
Matthew Fidler [aut] (<https://orcid.org/0000-0001-8538-6691>), Yuan Xiong [aut], Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>), Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>), Wenping Wang [aut, cre], Robert Leary [ctb], Mason McComb [aut] (<https://orcid.org/0000-0001-9871-8616>), Mirjam Trame [ctb], Teun Post [ctb], Richard Hooijmaijers [aut], Hadley Wickham [ctb], Dirk Eddelbuettel [cph], Johannes Pfeifer [ctb], Robert B. Schnabel [ctb], Elizabeth Eskow [ctb], Emmanuelle Comets [ctb], Audrey Lavenu [ctb], Marc Lavielle [ctb], David Ardia [cph], Daniel C. Dillon [ctb], Katharine Mullen [cph], Ben Goodrich [ctb]
Initial release

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