Random pedigree
Creates a random medical pedigree with specified number of generations.
randomPed(gen, lambda = 2, penetrances = c(0, 1, 1), naff = "last.gen", founder.mut = 1)
gen |
an integer in the interval |
lambda |
a positive numeric. For each descendant of the first
generation, the number of offspring is sampled from a Poisson distribution
with parameter |
penetrances |
a numeric of length 3, as in |
naff |
an integer specifying a lower bound on the number of affected individuals, or the character 'last.gen'. The latter produce a pedigree where at least one in the youngest generation is affected. |
founder.mut |
an integer, the number of disease alleles to be distributed among the founders. |
The function produces a random simple pedigree. Each founder is given at most one disease allele. At least one of the two top founders carries a disease allele.
A linkdat object.
Magnus Dehli Vigeland
plot(randomPed(3)) # gives error message: Not enough founder mutations ## Not run: randomPed(gen=4, penetrances=c(0,0,1), naff=2, founder.mut=1) ## End(Not run)
Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.