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qc_proteome_coverage

Proteome coverage per sample and total


Description

Calculates the proteome coverage for each samples and for all samples combined. In other words the fraction of detected proteins to all proteins in the proteome is calculated.

Usage

qc_proteome_coverage(
  data,
  sample,
  protein_id,
  organism_id,
  plot = TRUE,
  interactive = FALSE
)

Arguments

data

A data frame containing at least sample names and protein ID's.

sample

The column in the data data frame containing the sample name.

protein_id

The column in the data data frame containing protein identifiers such as UniProt accessions.

organism_id

The NCBI taxonomy identifier (TaxId) of the organism used. Human: 9606, S. cerevisiae: 559292, E. coli: 83333.

plot

A logical indicating whether the result should be plotted (default is TRUE).

interactive

A logical indicating whether the plot should be interactive (default is FALSE).

Value

A bar plot showing the percentage of of the proteome detected and undetected in total and for each sample. If plot = FALSE a data frame containing the numbers is returned.

Examples

## Not run: 
qc_proteome_coverage(
  data,
  sample = r_file_name,
  protein_id = pg_protein_accession,
  organism_id = 9606
)

## End(Not run)

protti

Bottom-Up Proteomics and LiP-MS Quality Control and Data Analysis Tools

v0.1.1
MIT + file LICENSE
Authors
Jan-Philipp Quast [aut, cre], Dina Schuster [aut], ETH Zurich [cph, fnd]
Initial release

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