Sampling algorithm for gbcd
Sampling algorithm for gbcd
gbcdRand(N, rho, K = 2)
N |
integer for the total sample size of the trial. |
rho |
nonnegative parameter which my be adjusted according to how strongly it is
desired to balance the experiment. If |
K |
number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment). |
A vector with the allocation sequence for a clinical trial.
It will contain a zero (resp. 1) at position i, when patient i
is allocated to treatment A (resp. B).
R. L. Smith (1984) Sequential treatment allocation using biased coin designs.
Journal of the Royal Statistical Society B,
46, 519-543.
W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley,
64-65
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