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rba_uniprot_coordinates

Get Genomic Coordinates of a Protein


Description

Using this function you can retrieve genomic Coordinates of a Protein by either providing the protein's UniProt accession or it's ID in a cross-reference database (Ensembl, CCDC, HGNC or RefSeq). You should provide either 'accession' alone or 'db_type' and 'db_id' together.

Usage

rba_uniprot_coordinates(accession = NA, db_type = NA, db_id = NA, ...)

Arguments

accession

UniProtKB primary or secondary accession.

db_type

cross-reference database name, Should be one of: "Ensembl", "CCDC", "HGNC" or "RefSeq".

db_id

Protein's ID in the cross-reference database

...

rbioapi option(s). Refer to rba_options's arguments documentation for more information on available options.

Details

For more information about how UniProt imports and calculates genomic coordinates data, see:
McGarvey, P. B., Nightingale, A., Luo, J., Huang, H., Martin, M. J., Wu, C., & UniProt Consortium (2019). UniProt genomic mapping for deciphering functional effects of missense variants. Human mutation, 40(6), 694–705. https://doi.org/10.1002/humu.23738

Value

A list with genome coordinates of your provided protein.

Corresponding API Resources

"GET https://ebi.ac.uk/proteins/api/coordinates/accession"
"GET https://ebi.ac.uk/proteins/api/coordinates/dbtype:dbid"

References

  • Andrew Nightingale, Ricardo Antunes, Emanuele Alpi, Borisas Bursteinas, Leonardo Gonzales, Wudong Liu, Jie Luo, Guoying Qi, Edd Turner, Maria Martin, The Proteins API: accessing key integrated protein and genome information, Nucleic Acids Research, Volume 45, Issue W1, 3 July 2017, Pages W539–W544, https://doi.org/10.1093/nar/gkx237

  • Proteins API Documentation

See Also

Examples

rba_uniprot_coordinates(accession = "P25942")


rba_uniprot_coordinates(db_type = "HGNC", db_id = "CD40")

rbioapi

User-Friendly R Interface to Biologic Web Services' API

v0.7.0
GPL-3
Authors
Moosa Rezwani [aut, cre, cph]
Initial release

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