An object of class modelorg.

An object of class reactId or character or integer containing reaction id's to constrain to zero.
Default: react_id(model).

An object of class reactId or character or integer containing reaction id's to constrain to zero.
Default: react_id(model).

A numeric vector containing the lower bounds for the reaction rates of reactions (variables) given in arguments react1 and react2. If set to NULL, all reactions will be constrained to zero.
Default: NULL.

A numeric vector containing the upper bounds for the reaction rates of reactions (variables) given in arguments react1 and react2. If set to NULL, all reactions will be constrained to zero.
Default: NULL.

A single Boolean value. If set to TRUE, every possible pairwise combination of reactions given in arguments react1 and react2 will be constrained to zero flux. If set to FALSE, arguments react1 and react2 must have the same length. The deletions will be computed pair-wise: first react1[1] and react2[1], second react1[2] and react2[2] and so on.
Default: FALSE.

A single Boolean value. If set to TRUE, exchange reactions will be excluded from the analysis. They are identified by the function findExchReact. Default: FALSE.

A single logical value. If set to TRUE, a warning will be generated, if not all optimizations ended successful.
Default: FALSE.

Further arguments passed to optimizer. Important ones are algorithm in order to set the algorithm to use or solverParm in order to set parameter values for the optimization software.