Flux Variability Analysis
Performs flux variability analysis for a given model.
fluxVar(model, react = c(1:react_num(model)), exex = FALSE, ...)
model |
An object of class |
react |
An object of class |
exex |
Boolean. Exclude exchange reactions from analysis. If set to |
... |
Further arguments passed to |
The algorithm is described in
sysBiolAlg_fv.
An object of class optsol_fluxVar. The first 1 to
n (with n being the number of elements in argument react)
solutions are from the minimizations, and the last n+1 to 2n
solutions are from the maximizations.
Gabriel Gelius-Dietrich <geliudie@uni-duesseldorf.de>
Maintainer: Mayo Roettger <mayo.roettger@hhu.de>
Becker, S. A., Feist, A. M., Mo, M. L., Hannum, G., Palsson, B. Ø. and Herrgard, M. J. (2007) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat Protoc 2, 727–738.
Schellenberger, J., Que, R., Fleming, R. M. T., Thiele, I., Orth, J. D., Feist, A. M., Zielinski, D. C., Bordbar, A., Lewis, N. E., Rahmanian, S., Kang, J., Hyduke, D. R. and Palsson, B. Ø. (2011) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat Protoc 6, 1290–1307.
Bernhard Ø. Palsson (2006). Systems Biology: Properties of Reconstructed Networks. Cambridge University Press.
data(Ec_core) fv <- fluxVar(Ec_core) plot(fv)
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