Produces a Model in Irreversible Format
The function mod2irrev produces a model with all reactions
moving in positive direction.
mod2irrev(model, exex = FALSE)
model |
An object of class |
exex |
Boolean. Exclude exchange fluxes (default: FALSE). |
The returned model consists only of reactions moving in positive
direction. Reactions with a negative direction in the original model
are transferred to positive direction; the corresponding reaction id
gets extended by “_r”.
Reversible reactions are split into two reactions. The corresponding
reaction ids gets extended by “_f”, or “_b”
indicating the original direction.
If exex = TRUE, the exchange reactions were obtained by
findExchReact.
An object of class modelorg_irrev.
Gabriel Gelius-Dietrich <geliudie@uni-duesseldorf.de>
Maintainer: Mayo Roettger <mayo.roettger@hhu.de>
Becker, S. A., Feist, A. M., Mo, M. L., Hannum, G., Palsson, B. Ø. and Herrgard, M. J. (2007) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat Protoc 2, 727–738.
Schellenberger, J., Que, R., Fleming, R. M. T., Thiele, I., Orth, J. D., Feist, A. M., Zielinski, D. C., Bordbar, A., Lewis, N. E., Rahmanian, S., Kang, J., Hyduke, D. R. and Palsson, B. Ø. (2011) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat Protoc 6, 1290–1307.
data(Ec_core) Ec_ir <- mod2irrev(Ec_core)
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