Class used by trialr to fit Wason & Seaman's Augmented Binary method in single arm trials with two post-baseline tumour assessments.
Class used by trialr to fit Wason & Seaman's Augmented Binary method in single arm trials with two post-baseline tumour assessments.
augbin_2t_1a_fit(num_patients, tumour_size, non_shrinkage_failure, fit)
num_patients |
Integer, the number of patients analysed. |
tumour_size |
matrix-like object containing tumour size measures, with rows representing patients and columns representing chronological assessment points. Column one is baseline. |
non_shrinkage_failure |
matrix-like object containing logical indicators of non-shrinkage failure, with rows representing patients and columns representing chronological assessment points. |
fit |
An object of class |
Wason JMS, Seaman SR. Using continuous data on tumour measurements to improve inference in phase II cancer studies. Statistics in Medicine. 2013;32(26):4639-4650. doi:10.1002/sim.5867
Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). European Journal of Cancer. 2009;45(2):228-247. doi:10.1016/j.ejca.2008.10.026
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