Description

Natrajan et al. (J. Pathology (2006) 210: 49 - 58) used array comparative genomic hybridization to obtain genome-wide DNA copy number data from 97 Wilms' tumor samples at 3288 markers. This matrix contains the DNA copy number data after applying the bias-correction procedure outlined in Bioinformatics (2011) 27(5) 678 - 685. Each row corresponds to DNA copy number from one subject at 3288 markers, while each column contains DNA copy number data for 97 subjects at one marker.

Usage

Format

A 97 by 3288 numeric matrix containing DNA copy number data, as described above.

Source

http://www.ebi.ac.uk/arrayexpress/ accession number E-TABM-10.

References

Natrajan, R., Williams, R.D., Hing, S.N., et al., Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse, J. Pathology (2006) 210: 49 - 58.

Walter, V., Nobel, A.B., and Wright, F.A., DiNAMIC: a method to identify recurrent DNA copy number aberrations in tumors, Bioinformatics (2011) 27(5) 678 - 685.