Enhances various R packages that support the design and simulation
of phase 1 dose-escalation trials, adding diagnostics to examine
the safety characteristics of these designs in light of expected
inter-individual variation in pharmacokinetics and pharmacodynamics.
See Norris (2020b), "Retrospective analysis of a fatal dose-finding
trial" <arXiv:2004.12755> and (2020c) "What Were They Thinking?
Pharmacologic priors implicit in a choice of 3+3 dose-escalation design"
<arXiv:2012.05301>.

Safety Diagnostics for Dose-Escalation Trial Designs

package-ubuntu-20.04-r-4.0.5#cran#precautionary-0.2-1

<dl>
<dt><code>dist</code></dt>
<dd>
<p>A list with <code>cdf</code>, <code>quantile</code> and <code>name</code> components
intended to provide that portion of the interface of <code>distr6::Lognormal</code>.</p>
</dd>
</dl>

package-ubuntu-20.04-r-4.0.5#cran#precautionary-0.2-1#docs#mtdi_lognormal-class

mtdi_lognormal-class

Description

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precautionary

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