Become an expert in R — Interactive courses, Cheat Sheets, certificates and more!
Get Started for Free

phase1_sim

Override escalation:::phase1_sim to incorporate latent toxicity tolerances


Description

Override escalation:::phase1_sim to incorporate latent toxicity tolerances

Usage

phase1_sim(
  selector_factory,
  true_prob_tox,
  sample_patient_arrivals = function(df) cohorts_of_n(n = 3, mean_time_delta = 1),
  previous_outcomes = "",
  next_dose = NULL,
  i_like_big_trials = FALSE,
  return_all_fits = FALSE
)

Arguments

selector_factory

A selector_factory object

true_prob_tox

A vector of toxicity probabilities for the doses defined in selector_factory

sample_patient_arrivals

A function implementing an arrivals process for trial enrollment

previous_outcomes

This may or may not apply in applications of package precautionary

next_dose

Undocumented

i_like_big_trials

I didn't choose this parameter name

return_all_fits

Don't do this


precautionary

Safety Diagnostics for Dose-Escalation Trial Designs

v0.2-1
MIT + file LICENSE
Authors
David C. Norris [aut, cre, cph] (<https://orcid.org/0000-0001-9593-6343>), Markus Triska [ctb]
Initial release
2021-01-12

We don't support your browser anymore

Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.