Enhances various R packages that support the design and simulation
of phase 1 dose-escalation trials, adding diagnostics to examine
the safety characteristics of these designs in light of expected
inter-individual variation in pharmacokinetics and pharmacodynamics.
See Norris (2020b), "Retrospective analysis of a fatal dose-finding
trial" <arXiv:2004.12755> and (2020c) "What Were They Thinking?
Pharmacologic priors implicit in a choice of 3+3 dose-escalation design"
<arXiv:2012.05301>.

Safety Diagnostics for Dose-Escalation Trial Designs

package-ubuntu-20.04-r-4.0.5#cran#precautionary-0.2-1

<p>Test performance of <code>draw_samples</code> function
</p>

<table summary="R argblock"><tr valign="top">
<td><code>n</code></td>
<td>
<p>Number of samples to draw</p>
</td>
</tr></table>

package-ubuntu-20.04-r-4.0.5#cran#precautionary-0.2-1#docs#test_draw_samples

test_draw_samples

Description

Usage

Arguments

precautionary

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