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rba_reactome_orthology

Get Orthologous (Computationally Inferred) Events


Description

Reactome incorporate manually curated human reactions and PANTHER's protein homology data to Computationally infer events in other eukaryotic species.

Usage

rba_reactome_orthology(event_ids, species_dbid, ...)

Arguments

event_ids

Human Reactome event ID(s) to retrieve their orthologous events.

species_dbid

Reactome database ID (DbId) of the target species. (e.g Mus musculus is 48892). Refer to rba_reactome_species or Reactome Data Schema: Entries: Species.

...

rbioapi option(s). Refer to rba_options's arguments documentation for more information on available options.

Details

In version 73 (11 June 2020), using an orthology-based approach, Homo sapiens events was projected to 18,654 orthologous pathways (with 81,835 orthologous proteins) in 15 non-human species.
Refer to Reactome Computationally Inferred Events for more information.

Value

List containing found Orthologous event(s) in your provided species and their pertinent information.

Corresponding API Resources

"POST https://reactome.org/ContentService/data/orthologies/ids/ species/speciesId"

References

  • Jassal B, Matthews L, Viteri G, Gong C, Lorente P, Fabregat A, Sidiropoulos K, Cook J, Gillespie M, Haw R, Loney F, May B, Milacic M, Rothfels K, Sevilla C, Shamovsky V, Shorser S, Varusai T, Weiser J, Wu G, Stein L, Hermjakob H, D'Eustachio P. The reactome pathway knowledgebase. Nucleic Acids Res. 2020 Jan 8;48(D1):D498-D503. doi: 10.1093/nar/gkz1031. PubMed PMID: 31691815.

  • Reactome Content Services API Documentation

See Also

Examples

rba_reactome_orthology(event_ids = c("R-HSA-6799198", " R-HSA-72764"),
    species_dbid = 49633)

rbioapi

User-Friendly R Interface to Biologic Web Services' API

v0.7.0
GPL-3
Authors
Moosa Rezwani [aut, cre, cph]
Initial release

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