Simulate PK data from a 1-compartment oral model
Simulate PK data from a 1-compartment oral model
pk_oral_1cmt(t, tau = 24, dose = 120, ka = 1, ke = 1, cl = 10, ruv = NULL)
t |
Time after dose |
tau |
Dosing interval |
dose |
Dose |
ka |
Absorption rate |
ke |
Elimination rate |
cl |
Clearance |
ruv |
Residual variability |
A vector of predicted values, with or without added residual variability
dat1 <- vpc:::pk_oral_1cmt(t = c(0:72), tau = 24, dose = 120,
ka = 1, ke = 1, cl = 10)
dat2 <- vpc:::pk_oral_1cmt(t = c(0:72), tau = 24, dose = 120,
ka = 1, ke = 1, cl = 10,
ruv = list(proportional = 0.1, additive = 0.1))Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.