Become an expert in R — Interactive courses, Cheat Sheets, certificates and more!
Get Started for Free

vpc

Create Visual Predictive Checks

Visual predictive checks are a commonly used diagnostic plot in pharmacometrics, showing how certain statistics (percentiles) for observed data compare to those same statistics for data simulated from a model. The package can generate VPCs for continuous, categorical, censored, and (repeated) time-to-event data.

Functions (33)

add_noise

Add noise / residual error to data

add_sim_index_number

Add sim index number

add_stratification

Adds stratification to data set

auto_bin

Calculate appropriate bin separators for vpc

bin_data

Function to bin data based on a vector of bin separators, e.g. for use in VPC

check_stratification_columns_available

Check whether stratification columns are available

compute_kaplan

Compute Kaplan-Meier statistics

compute_kmmc

Compute KMMC statistics

create_vpc_theme

Create new vpc theme

define_data_columns

Define data column defaults for various softwares

draw_params_mvr

Draw parameters from multivariate distribution

loq_perc

Calculate percentiles below / above lloq / uloq

new_vpc_theme

Create a customized VPC theme

pk_iv_1cmt

Simulate PK data from a 1-compartment iv model

pk_oral_1cmt

Simulate PK data from a 1-compartment oral model

plot_vpc

VPC plotting function

quantile_cens

Calculate quantiles respecting the censored data

read_table_nm

NONMEM output table import function

replace_list_elements

Replace list elements by name

rtte_obs_nm

Simulated RTTE data (1x)

rtte_sim_nm

Simulated RTTE data (100x)

show_default

Defaults for show argument

show_default_tte

Defaults for show argument for TTE VPC

sim_data

Simulate data based on a model and parameter distributions

simple_data

A small rich dataset

theme_empty

Empty ggplot2 theme

theme_plain

A nicer default theme for ggplot2

triangle_to_full

Lower to full triangle

vpc

VPC function

vpc-package

VPC package

vpc_cat

VPC function for categorical

vpc_cens

VPC function for left- or right-censored data (e.g. BLOQ data)

vpc_tte

VPC function for time-to-event (survival) data

vpc

Create Visual Predictive Checks

v1.2.2
MIT + file LICENSE
Authors
Ron Keizer <ronkeizer@gmail.com>
Initial release
2021-01-11

We don't support your browser anymore

Please choose more modern alternatives, such as Google Chrome or Mozilla Firefox.