xpose4

GAM functions for Xpose 4

Absolute conditional weighted residuals vs covariates for Xpose 4

Absolute population conditional weighted residuals vs population predictions for Xpose 4

Absolute value of the conditional weighted residuals vs. population predictions, conditioned on covariates, for Xpose 4

Absolute population weighted residuals vs population predictions, and absolute individual weighted residuals vs individual predictions, for Xpose 4

box and whisker plots of the absolute value of the individual weighted residuals vs. covariates

absolute value of the individual weighted residuals vs. the independent variable

Absolute individual weighted residuals vs individual predictions for Xpose 4

Absolute individual weighted residuals vs individual predictions, conditioned on covariates, for Xpose 4

Absolute individual weighted residuals vs population predictions or independent variable for Xpose 4

Absolute weighted residuals vs covariates for Xpose 4

Absolute value of (C)WRES vs. independent variable plot in Xpose4.

Absolute population weighted residuals vs population predictions for Xpose 4

Absolute population weighted residuals vs population predictions, conditioned on covariates, for Xpose 4

Model comparison plots, of absolute differences in goodness-of-fit predictors against covariates, for Xpose 4

Print tables or text in a grid object

Additional model comparison plots, for Xpose 4

Column-transformation functions for Xpose 4

Generic internal functions for Xpose 4

Additional goodness-of-fit plots, for Xpose 4

Autocorrelation of conditional weighted residuals for Xpose 4

autocorrelation of the individual weighted residuals

Autocorrelation of weighted residuals for Xpose 4

Basic goodness-of-fit plots, for Xpose 4

Basic model comparison plots, for Xpose 4

Function to create histograms of results from the bootstrap tool in PsN

Print summary information for a bootgam or bootscm

Import bootscm data into R/Xpose

Categorical observations vs. independent variable using stacked bars.

Categorical (visual) predictive check.

Generic table functions for Xpose 4

Change parameter scope.

Changes the name of an Xpose data item

Changes the label of an Xpose data item

Change Xpose variable definitions.

Functions changing variable definitions in Xpose 4

Functions changing miscellaneous parameter settings in Xpose 4

Data functions for Xpose 4

Compute the Conditional Weighted Residuals

Function to create mirror plots from the generic Xpose plotting commands

Create xpose.multiple.plot class.

This function creates the Xpose data classes ("xpose.data" and "xpose.prefs")

Histogram of conditional weighted residuals (CWRES), for Xpose 4

Quantile-quantile plot of conditional weighted residuals (CWRES), for Xpose 4

Conditional Weighted residuals (CWRES) plotted against covariates, for Xpose 4

Population conditional weighted residuals (CWRES) plotted against the independent variable (IDV) for Xpose 4

Box-and-whisker plot of conditional weighted residuals vs the independent variable for Xpose 4

Population conditional weighted residuals (CWRES) plotted against population predictions (PRED) for Xpose 4

Box-and-whisker plot of conditional weighted residuals vs population predictions for Xpose 4

Weighted residuals (WRES) and conditional WRES (CWRES) plotted against the independent variable (IDV)

Weighted residuals (WRES) and conditional WRES (CWRES) plotted against the population predictions (PRED)

Change in individual objective function value vs. covariate value.

Change in Objective function value vs. removal of individuals.

Change in individual objective function value 1 vs. individual objective function value 2.

Check through the source dataset to detect problems

Extract or assign data from an xpose.data object.

Prints the contents of an Xpose data object

Observations (DV), individual predictions (IPRED) and population predictions (IPRED) plotted against the independent variable (IDV), for Xpose 4

Observations (DV) plotted against the independent variable (IDV) for Xpose 4

Observations (DV) plotted against individual predictions (IPRED) for Xpose 4

Dependent variable vs individual predictions, conditioned on covariates, for Xpose 4

Dependent variable vs individual predictions, conditioned on independent variable, for Xpose 4

Observations (DV) plotted against population predictions (PRED) for Xpose 4

Dependent variable vs population predictions, conditioned on covariates, for Xpose 4

Dependent variable vs population predictions, conditioned on independent variable, for Xpose 4

Observations (DV) are plotted against individual predictions (IPRED) and population predictions (PRED), for Xpose 4

Exports Xpose graphics settings to a file.

Exports Xpose variable definitions to a file from an Xpose data object.

Internal functions for the VPC

Structured goodness of fit diagnostics.

Imports Xpose graphics settings from a file to an Xpose data object.

Imports Xpose variable definitions from a file to an Xpose data object.

Observations (DV), individual predictions (IPRED) and population predictions (PRED) are plotted against the independent variable for every individual in the dataset, for Xpose 4

Histograms of weighted residuals for each individual in an Xpose data object, for Xpose 4

Quantile-quantile plots of weighted residuals for each individual in an Xpose data object, for Xpose 4

Individual predictions (IPRED) plotted against the independent variable (IDV) for Xpose 4

Histogram of individual weighted residuals (IWRES), for Xpose 4

Quantile-quantile plot of individual weighted residuals (IWRES), for Xpose 4

Individual weighted residuals (IWRES) plotted against the independent variable (IDV) for Xpose 4

Kaplan-Meier plots of (repeated) time-to-event data

Make stacked bar data set.

Function to plot the coverage of the Numerical Predictive Check

Extract or set the value of the Nsim slot.

Plot the parameter or covariate distributions using a histogram

Plot the parameter or covariate distributions using quantile-quantile (Q-Q) plots

Plot scatterplot matrices of parameters, random parameters or covariates

Summarize individual parameter values and covariates

Parameters plotted against covariates, for Xpose 4

Plot parameters vs other parameters

Population predictions (PRED) plotted against the independent variable (IDV) for Xpose 4

Print an Xpose multiple plot object.

Function to create a histogram of results from the randomization test tool (randtest) in PsN

Random parameters plotted against covariates, for Xpose 4

Read (repeated) time-to-event simulation data files.

Reading NONMEM table files

Read the results file from a Numerical or Visual Predictive Check run in PsN

Read the vpctab file from PsN into Xpose

Read NONMEM output files into Xpose 4

Read NONMEM table files produced from simulation.

Resets Xpose variable definitions to factory settings

Print run summary in Xpose 4

Simulated prazosin Xpose database.

Function to create files for the simulated prazosin example in Xpose

Tabulate the population parameter estimates

Histogram of weighted residuals (WRES), for Xpose 4

Quantile-quantile plot of weighted residuals (WRES), for Xpose 4

Weighted residuals (WRES) plotted against covariates, for Xpose 4

Population weighted residuals (WRES) plotted against the independent variable (IDV) for Xpose 4

Box-and-whisker plot of weighted residuals vs the independent variable for Xpose 4

Population weighted residuals (WRES) plotted against population predictions (PRED) for Xpose 4

Box-and-whisker plot of weighted residuals vs population predictions for Xpose 4

Extract and set labels for Xpose data items.

Compare parameter estimates for covariate coefficients

Correlations between covariate coefficients

Distribution of difference in AIC

Plot of model size distribution for a bootgam or bootscm

Distribution of difference in OFV

OFV difference (optimism) plot.

Default function for calculating dispersion in xpose.gam.

Trace plots for conditional indices

Trace plots for conditional indices rper replicate number

Inclusion frequency plot

Inclusion frequency plot for combination of covariates.

Inclusion stability plot A plot of the inclusion frequency of covariates vs bootgam/bootscm iteration number. This plot can be used to evaluate whether sufficient iterations have been performed.

Plot of inclusion index of covariates.

Inclusion index individuals, compare between covariates.

Individual inclusion index

Define a scope for the gam. Used as default input to the scope argument in xpose.gam

Visual Predictive Check (VPC) using XPOSE

Xpose Visual Predictive Check (VPC) for both continuous and Limit of Quantification data.

Xpose visual predictive check for categorical data.

Function to ask the user for the name of a file

Title

Functions to create labels for plots

Create Xpose title text for plots.

Create an Xpose data object

Class xpose.data

Create a new graphical device for an Xpose plot.

Stepwise GAM search for covariates on a parameter (Xpose 4)

Displays the Xpose license and citation information

Create and object with class "xpose.multiple.plot".

Class for creating multiple plots in xpose

Xpose 4 generic function for plotting multiple lattice objects on one page

Default box-and-whisker panel function for Xpose 4

Default panel function for Xpose 4

Default histogram panel function for Xpose 4

Default QQ panel function for Xpose 4

Scatterplot matrix panel function for Xpose 4

The generic Xpose functions for box-and-whisker plots

The Xpose 4 generic functions for continuous y-variables.

The Xpose 4 generic functions for continuous y-variables.

The generic Xpose functions for QQ plots

The Xpose 4 generic functions for scatterplot matrices.

Class "xpose.prefs"

Summarize an xpose database

Print a pretty string.

Functions to create nice looking axes when using Log scales.

Classic menu system for Xpose 4

The Xpose Package

Extract or set the value of the Subset slot.

Extract and set Xpose variable definitions.