randomizeR: createParam – R documentation

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randomizeR

createParam

Representing any randomization procedure

Description

Represents any randomization procedure for a two-armed clinical trial.

Usage

createParam(method, N, mti, bc, rb, p, ini, add, filledBlock)

Arguments

`method`	method that is used to generate the (random) allocation sequence. It can take values `PBR`, `RAR`, `HAD`, `PWR`, `EBC`, `BSD`, `CR`, `TBD`, `UD`, and `MP`.
`N`	integer for the total sample size of the trial.
`mti`	maximum tolerated imbalance in patient numbers during the trial.
`bc`	vector which contains the lengths `k_1,...,k_l` of each block. This means that the vector `bc` will have one entry for each block.
`rb`	block lengths of the blocks that can be selected equiprobable at random.
`p`	success probability of the biased coin (e.g. in Efron's Biased Coin Design).
`ini`	integer representing the initial urn composition.
`add`	integer representing the number of balls that are added to the urn in each step.
`filledBlock`	`logical` whether the last block should be filled or not.

Details

Depending on the input of the user, createParam creates an object representing a randomization procedures for a two-armed clinical trial (see also randPar).

Value

S4object of the corresponding randomization procedure class.