randomizeR: hadaPar – R documentation

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randomizeR

hadaPar

Representing Hadamard Randomization

Description

Represents the randomization procedure Hadamard Randomization.

Usage

hadaPar(N, groups = LETTERS[1:2])

Arguments

`N`	integer for the total sample size of the trial.
`groups`	character vector of labels for the different treatments.

Details

Hadamard randomization has been proposed by R.A. Bailey. The key idea is to use the columns of a special Hadamard Matrix as a randomization scheme. The implemented algorithm uses the Hadamard Matrix with N=12 columns proposed in the paper, see references.

Value

S4 object of the class hadaPar.

Note

getProb and getAllSeq are currently only supported for hadaPar with total sample size N=12.

References

R.A. Bailey and P.R. Nelson (2003) Hadamard Randomization: A valid restriction of random permuted blocks. Biometrical Journal, 45, 554-60.