randomizeR: pbrPar – R documentation

Pricing

Become an expert in R — Interactive courses, Cheat Sheets, certificates and more!

Get Started for Free

Documentation

randomizeR

pbrPar

Representing Permuted Block Randomization

Description

Represents the randomization procedure Permuted Block Randomization.

Usage

pbrPar(bc, K = 2, ratio = rep(1, K), groups = LETTERS[1:K])

Arguments

`bc`	vector which contains the lengths `k_1,...,k_l` of each block. This means that the vector `bc` will have one entry for each block.
`K`	number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment).
`ratio`	vector of length `K`. The total sample number `N` and all used block lengths (`bc`) have to be divisible by `sum(ratio)`.
`groups`	character vector of labels for the different treatments.

Details

Fix the block constellation bc, the number of treatment groups K, and the vector of the ratio. Afterwards, in each block the patients are assigned according to the ratio to the corresponding treatment groups. All generated randomization sequences are equiprobable.

Value

S4 object of the class pbrPar.

References

W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley.